Inventions

Commercialised/Licensed out to Indian Medtech companies:

1. Paranasal sinus dilatation system (Sinucare):

A low cost sinus dilatation system using tools available in the ENT office                                                                Need Addressed: 1 in 8 Indians suffer from chronic sinusitis who respond poorly to oral medications. Most patients are compelled to take a more invasive FESS surgery rather than a less invasive balloon dilatation because the latter is very expensive Problem: Delay in definitive care for chronic sinusitis can lead to spread of infection into the eyes and brain Inventors: Dr. Jagdish Chaturvedi, Dr. Sunil Narayan Dutt, Pooja Kadambi, Andrew logan Patent: Indian Patent – Device and method for dilating paranasal sinus opening- 316/CHE/2014 (Read PatentStatus: Early commercialization to 100+ leading ENT surgeons


2. VAP management device (VAPcare):

A device to reduce ventilator associated pneumonitis in patients with prolonged intubation                               Need Addressed: It is difficult to clear out secretions from around the endotracheal tube effectively Problem: Pooling of secretions precipitates infection and increases the chances for development of ventilator associated pneumonitis Inventors: Dr. Jagdish Chaturvedi, Nitesh Jangir, Nachiket Deval, Dr. Vimal Kishore, Dr. Raghuvendra, Dr. Sajid Mohammed, Ramakrishna Pappu Patent: Indian Patent – Device and Method for Removal of secretions to prevent Ventilator Associated Pneumonia – 3988/CHE/2014, US Patent no 20160045698 (Read patent) Company formed: Coeo Labs Private Limited in August 2014 Status: Early commercialization reaching 5 major hospitals.


3. Mechanical CPAP device (Saans):

A low cost mechanical CPAP device for asphyxiated babies during transport                                              Need Addressed: 30% of newborn babies with Respiratory Distress Syndrome die every year  while being transported to a higher centre due to the lack of a low cost easy to use CPAP device Problem: If adequate pressure is not maintained within the lungs it leads to alveolar collapse Inventors: Dr. Jagdish Chaturvedi, Nitesh Jangir, Dr. Chetan AC, Dr. Data Santorino, Dr. Kris Olsen, Khallid Mohammed, Srivatsa K, Mhd. Yousuf Patent: Indian Patent – Device and method for providing mechanical positive airway pressure – 3558/CHE/2014  Status: Early Commercialization with 10 early adopters.


4. Ear, nose & throat Multiscope Recorder (ENTraview):

Entraview_1  A low cost, tri-purpose hand held device that allows portable ear nose throat endoscopy and recording               Need Addressed: Patients from low resource settings are examined using ancient methods with mirrors and head-lamps causing high error rates Problem: More than 20% of the population suffers from ENT diseases and approx. 90% are treated without endoscopic visualisation Inventor: Dr. Jagdish Chaturvedi Patent: Indian Patent – Ear Nose Throat Multi-scope Recorder Application Number 1293/CHE/2010 A (Read patent) Licensee: Licensed out to Icarus Nova Discovery Private Limited (website) in October 2013 Status: Commercialized with over 200,000 patients screened


5. Thoracocentesis device (Thorashield):

A safer disposable kit for evacuation of pleural fluid (fluid collection)                                                                   Need Addressed: Currently, clinicians use IV needles and collection bottles to evacuate pleural fluid in an unstandardised manner Problem: Use of non standardised sharp needles for evacuation of pleural fluid without adequate stabilization can lead to injury to the lungs and cause pneumothorax Inventors: Dr. Jagdish Chaturvedi, Dr. Vaisakh NJ, Nitesh Jangir, Ankita Kashyap, Saaransh Jain, Dr. Karan Madan, Dr. Randeep Gulleria Patent: Indian Patent –  Aspiration device Application Number – 2639/DEL/2013 (Read Patent) Licensee: Licensed out to Mecmaan Healthcare Private Limited (website) in December 2013 Status: Commercialized in India and Europe6


6. Nasal foreign body extractor (Noxeno):

 Low skill nasal foreign body extractor for non ENT practitioners                                                                        Need Addressed: There is no standardised tool available today for nasal foreign body removal and skill requirement for removal is very high Problem: Approx. 38 million children have impacted nasal foreign bodies every year. More than 80% of these children undergo failed attempts of removal by general practitioners and pediatricians due to the lack of a simple and easy to use tool. The removal then needs to be performed under general anesthesia  Inventors: Dr. Jagdish Chaturvedi, Dr. Jonathan Pillai, Siddhartha Joshi, Siraj Bagwan, Dr. Suresh C Sharma, Dr. Kapil Sikka Patent: Indian Patent – Removing foreign objects from the nasal cavity Application Number- 3838/DEL/2012 (Read PatentLicensee: Licensed out to InnAccel Consulting Services Private Limited (website) in December 2013 Status: Pre-Commercialization


7. Abdominal paracentesis device (Parasafe):

Parasafe A safer disposable kit for evacuation of abdominal ascites (fluid collection)                                                         Need Addressed: Currently, clinicians use IV needles and collection bottles to evacuate ascitic fluid in an unstandardised manner Problem: Use of non standardised sharp needles for evacuation of ascitic fluid can lead to injury to the bowel and other abdominal contents Inventors: Dr. Jagdish Chaturvedi, Dr. Jonathan Pillai, Siddhartha Joshi, Siraj Bagwan, Dr. Govind Makharia, Dr. Pramod Garg, Dr. Haneesh Patent: Indian Patent – Abdominal paracentesis device Application Number- 3839/DEL/2012 Licensee: Licensed out to Mecmaan Healthcare Private Limited (website) in December 2013 Status: Pre-Commercialization


8. Nasogastric insertion guide (Accufeed):

AccufeedLow cost guiding device for accurate nasogastric tube insertion                                                                              Need Addressed: Multiple attempts are often required while introducing a nasogastric tube in patients who have lost sensation in their throat Problem: Incorrect nasogastric tube insertion into the lungs can lead to fatal aspiration pneumonitis Inventors: Dr. Jagdish Chaturvedi, Agyeya Dwivedi, Medha Tyagi, Himanshu Gupta, Neha Shetty, Dr. Govind Makharia, Dr. Pramod Garg Patent: Assistive device for enteral tubes Application Number – 2652/DEL/2013 (Read Patent) Licensee: Licensed out to Mecmaan Healthcare Private Limited (website) in December 2013 Status: Pre-Commercialization


Formed start up companies in India/presently under development:

9. Liver biopsy device (Bioscoop):

Low cost, safer liver biopsy tool that reduces the risk of internal bleeding                                                              Need Addressed: Currently, clinicians avoid liver biopsies due to fear of internal bleeding and hence often treat empirically Problem: Burden of diseases such as chronic Hepatitis increases due to faulty management resulting from lack of biopsies Inventors: Dr. Jagdish Chaturvedi, Dr. Jonathan Pillai, Siddhartha Joshi, Siraj Bagwan, Dr. Govind Makharia, Dr. Pramod Garg, Dr. Haneesh Patent: Indian Patent – Device and method for liver biopsy Application Number- 3881/DEL/2012 (Read Patent) Company formed: Indiolabs Private Limited (website) in September 2013 Status: Pre-Clinical Trials


10. Hand sanitization device (Hanitizer):

Hanitizer01Wall mounted, no touch operated hand sanitizer dispensing device                                                                   Need Addressed: There is poor compliance to maintaining hand hygiene by healthcare professionals Problem: Poor hand hygiene contributes to hospital acquired infections  Inventors: Dr. Jagdish Chaturvedi, Aanan Khurma, Saurabh Bagh, Agyeya Dwivedi Patent: Indian Patent – Hand sanitizer dispensing device – 3673/DEL/2013 Company formed: Observe Design Private Limited (website) in March 2014 Status: Pre-Clinical Trials


11. Epistaxis controlling device (Nasoplast):

Disposable nose pincher with adsorbent to stop nasal bleeds                                                                             Need Addressed: Bleeding from the nose is a common problem for which there is poor awareness on how to provide correct first aid Problem: Delayed control of nasal bleeding precipitates risk for infection Product developed for: Icarus Nova Discovery Private Limited (website)  Status: Pre-Clinical Trials


Prototypes with discontinued development due to challenges

12. ICP management device (ICPcure):

ICPA device to temporarily manage rising intra cranial tension in head injury patients                                                Need Addressed: Patients with head injury have rising intracranial pressure and need immediate neurosurgical intervention. This is not always available due to the large number of head injury cases with limited neurosurgical care Problem: Rising intracranial pressure causes herniation of the brainstem and results in respiratory depression and death Inventors: Dr. Jagdish Chaturvedi, Nitesh Jangir, Nachiket Deval, Dr. Vimal Kishore, Dr. Raghuvendra, Dr. Sajid Mohammed, Ramakrishna Pappu Patent: Indian Patent – Device and method for raised intracranial pressure (Co-inventor)- 3991/CHE/2014 Company formed: Coeo Labs Private Limited in August 2014 Status: Early prototype Challenge: Hospital processes non-compliant – ER physician presently not permitted to carry invasive intra-cranial procedures in ER


13. An Objective Behavioural Audiometry Device (Aawaazz):

Aawaazz prototype 1An objective way to perform Behavioural Audiometry                                                                                  Need Addressed: Only 20% of 25 Million Newborns in India are screened for hearing loss in India Problem: The detection of hearing loss is after the age of 5, 90% of the times, leading to permanent speech development delay Inventors: Dr. Jagdish Chaturvedi, Abhishek Appaji M, A. Saravanan, Dilip S , Rishya. P. Murthy, Tejaswini v, Diksha Kushwaha, Vatsalya Ahuja, Randhir Singh, Ashfaq Ashraf, Viveka Santhosh Reddy C, Adithya Pasupuleti Status: Pre-clinical studies Challenge: Funding grants unavailable and engineering team unavailable


14. Adaptive noise cancellation for Tinnitus (ShanTi):

An effective way to reduce tinnitus                                                                                          

Need Addressed: A huge population in India suffer from a disabling condition which produces continuous ringing sensation in the ears called Tinnitus Problem: Ineffective and expensive management options available today for Tinnitus Inventors: Dr. Jagdish Chaturvedi, Shreya, Shreyas, Madhuri  Status: Early prototype Challenge: Early results on patients inconsistent due to lack of scientific understanding within the available literature


15. Medicine management box (Saakar Kit):

SaakarA space management device that helps manage medications when delivered to patients at sub centres                 Need Addressed: Medicines are delivered from Primary Healthcare Centre’s (PHC) to sub centres once every week and medications need to be carried Problem: Many patients do not receive the medications they need because of mismanaged storage and distribution Inventors: Dr. Jagdish Chaturvedi, Dr. Jonathan Pillai, Siddhartha Joshi, Siraj Bagwan, Dr. Sanjay Rai Patent: Indian Patent – Carrying case for storage and delivery of medicines and vaccines – 2631/DEL/2013 Status: Advanced prototype Challenge: Core team unavailable to lead commercialization


16. Esophageal varices management device (Variseal):

VarisealAn easy to administer upper GI bleeding management device                                                                             Need Addressed: It is very difficult to apply tamponade and control upper Gi bleeding. Existing devices require significant training. Problem: Failure to stop profuse upper GI bleeding can lead to hypovolemic shock and death Inventors: Dr. Jagdish Chaturvedi, Dr. Jonathan Pillai, Siddhartha Joshi, Siraj Bagwan, Dr. Govind Makharia, Dr. Pramod Garg, Dr. Haneesh Patent: Indian Patent – Radial inward compression of esophagus  Application Number- 3853/DEL/2012  Status: Early prototype Challenge: Extensive animal testing required. Lack of expertise to conduct animal studies and team to lead development


17. Hip OA injection assisting device (Accuhip):

AccuhipAccurate guidance for injections into the hip joint                                                                                          Need Addressed: Younger patients with osteoarthritis of the hip who are not covered under insurance for hip replacement need injections for lubrication of their joints Problem: Inaccurate injections can cause nerve and vascular injury resulting in permanent damage  Inventors: Dr. Jagdish Chaturvedi, Ankur Giggas, Michael H, Mike H, Katharina Schmidt,  Kristine Boucher Patent: US Patent – Method and system of treating osteoarthritis hip Application Number: 61609362 Status: Early prototype Challenge: Core team discontinued development


18. Bowel cleansing device (Magnabelt):

MagnabeltMagnetic belt to clean bowel prior to colonoscopy                                                                                               Need Addressed: Patients require adequate cleansing of their bowels prior to colonoscopy in order to increase the accuracy of diagnosis  Problem: Poor bowel preparation can lead to missing out of important lesions Inventors: Dr. Jagdish Chaturvedi, Dr. Jonathan Pillai, Siddhartha Joshi, Siraj Bagwan, Patent: US Patent – Methods and devices for cleaning the bowel of fecal matter prior to imaging and Therapeutic Intervention, to aid visualization and therapy App#: 61658169 Status: Early prototype Challenge: Core team discontinued development